Abstract:Twenty-first Century is a multicultural society, in the context of the modern trend in addition to pay attention to students' knowledge and technology teaching, colleges and universities also need to always pay attention to the changes of students' thought, and strengthen ideological work to train more talents with more advanced technology and high-quality for the society. This paper regards the ideological work as the research object, sees Xi Jinping's socialist ideology with Chinese characteristics of the new era as foundation, and explores a new approach to ideological work in colleges and universities, based on the development of social science and technology and present situation of colleges and universities.